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Analysis of the CEDIRA and VANDET-regulated transcriptomes in human non-small cell lung cancer (NSCLC) xenografts
Overview
Dataset Name :
Analysis of the CEDIRA and VANDET-regulated transcriptomes in human non-small cell lung cancer (NSCLC) xenografts
Description :
Human NSCLC xenografts were recovered from mice treated with or without VANDET (50 mg/kg orally daily) or CEDIRA (6 mg/kg orally daily).
Dataset Type :
Transcriptomic
Release Date :
January 23, 2018
DOI :
10.1621/yISdebuoaY
Version :
This is Version 1.0 of an annotated derivative of the original dataset, which can be found in GSE64472
Dataset Citation :
Cascone T, Kadara HN and Liu W (2017) Analysis of the CEDIRA and VANDET-regulated transcriptomes in human non-small cell lung cancer (NSCLC) xenografts, v 1.0 Signaling Pathways Project Datasets. 10.1621/yISdebuoaY
Download Citation :

Associated Article :
Cascone T, Xu L, Lin HY, Liu W, Tran HT, Liu Y, Howells K, Haddad V, Hanrahan E, Nilsson MB, Cortez MA, Giri U, Kadara H, Saigal B, Park YY, Peng W, Lee JS, Ryan AJ, Jüergensmeier JM, Herbst RS, Wang J, Langley RR, Wistuba II, Lee JJ and Heymach JV (2017) The HGF/c-MET Pathway Is a Driver and Biomarker of VEGFR-inhibitor Resistance and Vascular Remodeling in Non-Small Cell Lung Cancer. Clin. Cancer Res. 23 5489-5501 View Abstract | View PubMed
The HGF/c-MET Pathway Is a Driver and Biomarker of VEGFR-inhibitor Resistance and Vascular Remodeling in Non-Small Cell Lung Cancer.

Experiments

There are 2 Experiments for this dataset. Up to the 50 up and down p < 0.05 FDR data points are displayed for each. Please download the dataset to view all data points.

  • 1 | CEDIRA sensitive vs CEDIRA resistant - human
  • 2 | VANDET sensitive vs VANDET resistant - human
Gene List
Experiment Information
Name : CEDIRA sensitive vs CEDIRA resistant - human
Description :

Human NSCLC xenografts were recovered from mice sensitive or resistant to treatment with CEDIRA (6 mg/kg orally daily).

Tissue/Cell line : NSCLC, xenografts
Species : Human
Additional Information